‘Made in India’ Supernova Stent Proven Effective in Acute Stroke Care Through GRASSROOT Trial
Landmark Indian Study Validates Indigenous Stent Retriever for Life-Saving Stroke Intervention
Marengo CIMS Hospital Highlights India’s Breakthrough Homegrown Stroke Device
Landmark GRASSROOT Trial Validates ‘Made in India’ Supernova Stent Retriever
- Bilkul Online
- Ahmedabad, December 18, 2025
India has achieved a significant milestone in advanced stroke care with the successful completion of the GRASSROOT Trial, a landmark multicentre clinical study evaluating the Supernova Stent Retriever for patients suffering from acute ischemic stroke caused by large vessel occlusion.
This breakthrough reinforces India’s growing self-reliance in high-end neurovascular care, with the device designed by Indian engineers, clinically validated in India, and aligned with the ‘Make in India’ vision.
Eight Indian Stroke Centres Deliver Robust Clinical Evidence
The GRASSROOT Trial was conducted across eight leading stroke centres in India, including Marengo CIMS Hospital, Ahmedabad, generating strong Indian clinical data for an indigenously developed neurovascular device.
The study demonstrated high rates of successful vessel recanalisation, favourable first-pass success, and encouraging functional recovery at 90 days, while maintaining a low complication profile—outcomes comparable with global standards.
‘Made in India’ Device for Acute Brain Stroke Care
The Supernova Stent Retriever marks a major advancement by confirming that India now has a domestically developed stent for brain vessels used in acute stroke intervention. By addressing affordability and accessibility, the innovation fills a critical gap in India’s stroke care ecosystem.
Stroke remains one of the leading causes of death and long-term disability in the country, and timely access to mechanical thrombectomy can be life-saving. Indigenous solutions such as Supernova directly strengthen India’s emergency stroke response capabilities.
Clinical Leaders Speak on the Trial’s Impact
Dr Mukesh Sharma, Principal Investigator of the GRASSROOT Trial and Director – Neurointervention & Stroke, Marengo CIMS Hospital, said, “The GRASSROOT Trial is a game-changer for stroke care in India. High reperfusion rates with excellent safety outcomes mean more patients can now access life-saving mechanical thrombectomy within critical time windows, especially in resource-constrained settings.”
Dr R. Shankaran, Unit Medical Director, Marengo CIMS Hospital, added, “This study proves that world-class outcomes are achievable through indigenous innovation. It strengthens our confidence in delivering advanced, timely, and affordable stroke interventions for Indian patients.”
Strengthening India’s Vascular Emergency Ecosystem
Dr Keyur Parikh, Interventional Cardiologist and Chairman, Marengo CIMS Hospital, stated,
“India urgently needs scalable and cost-effective solutions for complex vascular emergencies. The Supernova device and the GRASSROOT Trial represent innovation driven by Indian clinical realities and backed by robust scientific evidence.”
Commitment to Evidence-Based, Patient-First Innovation
Dr Raajiv Singhal, Founding Member, Managing Director & Group CEO, Marengo Asia Hospitals, said, “At Marengo Asia Hospitals, innovation is anchored in patient outcomes, evidence, and real-world impact. This milestone reflects our patient-first philosophy and our commitment to advancing stroke care through strong Indian clinical evidence. By teaching, training, and treating in equal measure, we are building a sustainable healthcare ecosystem grounded in trust and outcomes.”
A Critical Step Forward for India’s Stroke Care Infrastructure
With nearly 1.7 million new stroke cases reported annually in India, indigenous, evidence-backed innovations such as the Supernova Stent Retriever represent a crucial step in strengthening the nation’s stroke care infrastructure—an effort Marengo CIMS Hospital continues to lead from the front.
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